dd-mice in Seattle : satisfaction theory in pictures

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2005: dopamine-deficient mice running a T-maze in Seattle.
(the picture is inspired by Siobhan Robinson, Suzanne Sandstrom, Victor Denenberg and Richard Palmiter from the Seattle's Howard Hughes Medical Institute)

phase 1: training

Appling "satisfaction theory" to T-maze run. You may want to replace "milk sucking" by "food-turn in the T-maze"...
learn

phase 2: test

recall

comments:

Day 1: after a caffeine intake, DD-mice run the maze "mechanically" and they eat food just using a reflex to gnaw and swallow when food is just under their nose?
Day 2: after an L-dopa shot:
food-turn = pleasant turn
DD-mice recall/choose the pleasant turn.

speculations:

1.. pleasure serves to choose
the best option from (lay down -- run left -- run right -- ...).
2.. satisfaction links pleasure to some previously perceived patterns.
Day-1: satisfaction links [run-and-food-turn-in-maze] to [pleasure]
Day-2: pleasure make mice recall the [run-turn-food] action.
A first time is always neutral-tasteless? Even make love?!
Well.. it seems so.. Wouldn't it explain frigid women? No first times satisfaction, no pleasure, no more sex.. a downwards spiral.
Many people run for pleasure, but in their perfectionism and goal seeking, they lack satisfaction, so they ruin pleasure links, and they end up depressed and the only options remaining are aggression or escaping fear. That's why Buda imagined an approach "be goal oriented, but do not desire the pleasant goal" and that's why our civilization made best progress in military technology (fear and aggression driven).

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